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Analyses were performed in SAS 9.3 (SAS Institute)

A common complaint heard from nicotine-dependent men and women is that their hands and feet are always cold

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Among those current smokers, 63 (6%) presented one or more tar staining on the hand

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While the first example is far more common, guidance from guidance from MedicineNet tells us the second example is potentially more serious, with causes including dehydration, vitamin deficiency or illness